But in studies where women were given anti-herpes drugs to decrease their lesions, there was no decrease in transmission.
This treatment (a ribozyme) has been shown to block Herpes Simplex Virus type 1 (HSV-1) infections.
Here we propose to test the ribozyme for its ability to block recurrent disease.
Most adults have contracted hsv-1, herpes simplex 1, and many are asymptomtic so they don't even know they have it. In the United States, 16 percent of adults are HSV-2 seropositive, but only 10 percent to 25 percent of persons with HSV-2 infection have recognized genital herpes. Specifically, they were: Reference: Archives of Ophthalmology Young RC, et al "Incidence, recurrence, and outcomes of herpes simplex virus eye disease in Olmsted County, Minnesota, 1976-2007: The effect of oral antiviral prophylaxis" Arch Ophthalmol 2010; 128(9): 1178-1183.
Moreover, most HSV-2 infections are acquired from persons without a clinical history of genital herpes," reports Dr. "Subclinical genital shedding rates were higher in persons with symptomatic infection compared with asymptomatic infection (2,708 of 20,735 [13.1 percent] vs. However, the median [midpoint] amount of HSV detected during subclinical genital shedding episodes was similar in persons with symptomatic and asymptomatic infection," Wald announced. The University of New Mexico (UNM), Brown University, and House Ear Institute (HEI) have developed a new method to observe HSV-1 infections growing in cells.
In lab studies it has been determined that growth and recurrences of HSV-1 are linked to the cognitive decline in Alzheimer's patients.